Search results for " liver imaging"

showing 3 items of 3 documents

Neoangiogenesis-related genes are hallmarks of fast-growing hepatocellular carcinomas and worst survival. Results from a prospective study

2016

Objective The biological heterogeneity of hepatocellular carcinoma (HCC) makes prognosis difficult. We translate the results of a genome-wide high-throughput analysis into a tool that accurately predicts at presentation tumour growth and survival of patients with HCC.Design Ultrasound surveillance identified HCC in 78 (training set) and 54 (validation set) consecutive patients with cirrhosis. Patients underwent two CT scans 6 weeks apart (no treatment in-between) to determine tumour volumes (V-0 and V-1) and calculate HCC doubling time. Baseline-paired HCC and surrounding tissue biopsies for microarray study (Agilent Whole Human Genome Oligo Microarrays) were also obtained. Predictors of su…

AdultMale0301 basic medicinemedicine.medical_specialtyTime FactorsCarcinoma HepatocellularTime FactorMicroarrayHepatocellular carcinomamolecular carcinogenesisGastroenterologyliver imagingHEPATOCELLULAR CARCINOMA; LIVER IMAGING; MOLECULAR CARCINOGENESIS; MOLECULAR ONCOLOGY; Adult; Aged; Aged 80 and over; Carcinoma Hepatocellular; Disease Progression; Female; Humans; Liver Neoplasms; Male; Middle Aged; Neovascularization Pathologic; Prospective Studies; Survival Rate; Time Factors; Tumor Burden; Medicine (all); Gastroenterology03 medical and health sciencesmolecular oncology0302 clinical medicineHepatocellular carcinoma liver imaging molecular carcinogenesis molecular oncologyInternal medicinemedicineCarcinomaHumansDoubling timeProspective StudiesProspective cohort studySurvival rateAgedAged 80 and overNeovascularization Pathologicbusiness.industryProportional hazards modelLiver NeoplasmsGastroenterologyMiddle Agedmedicine.diseaseTumor BurdenSurvival RateProspective Studie030104 developmental biologyQuartileLiver Neoplasm030220 oncology & carcinogenesisHepatocellular carcinomaDisease ProgressionFemalebusinessHumanGut
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Optimizing Liver Division Technique for Procuring Left Lateral Segment Grafts: New Anatomical Insights.

2021

Left liver lobe (left lateral segment) grafts (LLG) is currently the most commonly used graft to transplant children (2/3 of cases currently in Europe); it is prepared by liver division (DL) in both living (LD) and deceased donors (DD) settings. Technically speaking, classical DL is through the parenchyma of segment IV - dividing the main left glissonean pedicle left to the main biliary confluence (trans-hilar (TH) approach): historically, this technique was introduced by Bismuth and Pichlmayr in 1988 in DD setting, and applied one year later for the first successful living donor transplantations by Strong (Figure 1).

Transplantationmedicine.medical_specialtyHepatologybusiness.industrymedicine.medical_treatmentLiver transplantation living donor liver transplantation liver imaging. pediatric liver transplantationLiver transplantationLiving donorSurgeryLiver TransplantationLiverLeft liver lobeParenchymaLiving DonorsMedicineHepatectomyHumansSurgeryLateral segmentbusinessLiving donor liver transplantationLiver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
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Imaging features of histological subtypes of hepatocellular carcinoma: Implication for LI-RADS

2021

Background & Aims The histopathological subtypes of hepatocellular carcinoma (HCC) are associated with distinct clinical features and prognoses. This study aims to report Liver Imaging Reporting and Data System (LI-RADS)-defined imaging features of different HCC subtypes in a cohort of resected tumours and to assess the influence of HCC subtypes on computed tomography (CT)/magnetic resonance imaging (MRI) LI-RADS categorisation in the subgroup of high-risk patients. Methods This retrospective institutional review board-approved study included patients with resected HCCs and available histopathological classification. Three radiologists independently reviewed preoperative CT and MRI exams. T…

medicine.medical_specialtyHepatocellular carcinomaALT alanine transaminaseComputed tomographyRC799-869AST aspartate aminotransferaseOS overall survivalHistopathological subtypeMagnetic resonance imagingNOS-HCC not otherwise specified hepatocellular carcinomaInternal MedicinemedicineImmunology and AllergyIn patientComputed tomographyLI-RADS Liver Imaging Reporting and Data SystemLiver imagingHepatologymedicine.diagnostic_testbiologyUS ultrasoundbusiness.industryNot Otherwise SpecifiedGastroenterologyTIV tumour-in-veinMagnetic resonance imagingHBP hepatobiliary phaseDiseases of the digestive system. Gastroenterologymedicine.diseasedigestive system diseasesHistopathological subtypesCT computed tomographyRFS recurrence-free survivalAlanine transaminaseHepatocellular carcinomaSH-HCC steatohepatitic hepatocellular carcinomaCohortMTM-HCC macrotrabecular-massive hepatocellular carcinomabiology.proteinLI-RADSRadiologyAPHE arterial phase hyperenhancementbusinessHCC hepatocellular carcinomaMRI magnetic resonance imagingResearch ArticleJHEP Reports
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